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Concomitant MAO inhibitors: TRD-Contin should be employed with terrific caution in sufferers taking MAO inhibitors, given that tramadol inhibits the uptake of norepinephrine and serotonin.Abide by sufferers acquiring tramadol hydrochloride and any CYP2D6 inhibitor for the chance of serious adverse activities which includes seizures and serotonin sy

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